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  Home › Fitness & Health › Nutrition & Nourishment
   
 

Glyconutrients, Disease and the Immune System

   

Author: Patricia Howitt

The importance of glyconutrients is still being fully understood.

A glyconutrient is a dietary nutrient composed of a sugar. According to scientific research there are eight simple dietary sugars (monosaccharides) that are now known to form the very words of life at the cellular level. Because of the complexity of their carbohydrate structure, these sugars are able to combine with proteins to create glycoproteins that coat the surfaces of cells. Glycoproteins function as cellular recognition molecules that communicate the messages a body needs to function in health.

Of the 200 or so saccharides or carbohydrates found in plants, only these eight have been found to be essential:

Mannose: Research suggests mannose eases inflammation in rheumatoid arthritis. It is also shown to lower blood sugar and triglyceride levels in diabetics.

Galactose: Helps in wound healing and long-term memory formation.

Fucose: Guards against respiratory tract infections and inhibits allergic reactions. Research suggests the sugar is active against viruses including herpes and the AIDS virus. Fucose is abundant in breast milk.

Xylose: An antibacterial and antifungal. It may help prevent cancer of the digestive tract. It is often used as a substitute for corn syrup and sucrose. Xylose does not cause dental cavities.

Glucose: A potent, fast-energy source. Enhances memory and stimulates calcium absorption. Too much or too little glucose leads to problems.

N-Acetyl glucosamine: Glucosamine, a metabolic product of n-acetyl glucosamine, helps repair cartilage, decreases pain and inflammation, and increases range of motion in osteoarthritis. N-acetyl glucosamine plays a vital role in learning, and works against tumors and HIV.

N-acetyl neuraminic acid: This monosaccharide is abundant in breast milk, and important for brain development and learning. It has been shown to inhibit strains of influenza viruses more effectively than many prescription anti-virals. It influences blood coagulation and helps lower LDL (bad cholesterol) levels and raise HDL (good cholesterol) levels.

N-acetyl galactosamine: Studies on this monosaccharide are limited. We do know that lower-than-normal levels have been found in heart disease patients.

These Carbohydrates form combination molecules that have specific functions in the body:

Glycoproteins are molecules made of sugars and proteins and they are found coating the surface of every cell in the body that contains a nucleus. One of their functions is to assist the immune system in detecting and fighting such threats as viruses, toxins and bacteria.

Glycolipids are molecules made of sugars and fats. The central and peripheral nervous systems and the brain are rich in many specialized lipids, many of them complex lipids involved in signalling mechanisms. All these lipids are synthesized from glucose and other metabolites provided by the blood.

We tend to think of "sugars" as being fuel for our bodies, rather than having any structural significance. You can see that these special sugars are more important to our bodies than their name might indicate. As can be seen from the brief descriptions of each of the sugars above, they have very important roles to fulfil in keeping the integrity of our body structures intact.

Here are some more of the varied functions of glycoproteins and glycolipids:

to help retain bone density and muscle mass;

to assist the functions of the brain and nervous system from memory and sleep to anxiety and depression;

to help the body with healing by their beneficial effect on the immune system;

to provide the means of communication between cells that is essential to most bodily functions, which because of the structural complexity of their carbohydrate structure they are well adapted to do.

The different carbohydrate molecules combine within our bodies to make many cellular recognition "words". These precisely shaped words protrude from cell surfaces and are recognized and understood (or not understood) by neighbouring cells through the sense of touch.

A great variety of diseases, including many autoimmune diseases, have been found to be associated with altered imperfect formation and functioning of cell surface glycoproteins.

The important thing to realise is that most of these essential glyconutrients are no longer found in abundance in the standard modern diet. Unlike our ancestors, we now have to deal with increasing pollution together with the declining nutritional value of our food. This means we have to find a way of supplementing the special carbohydrates our bodies need for creating these essential glycoproteins and glycolipids that are so important to our systems.

Case studies have shown the effectiveness of glyconutrient supplementation in the treatment of some serious and wide-ranging diseases: streptococcal disease, toxic shock syndrome, Pemphigus vulgaris (a serious auto-immune blistering disorder of the skin and mucous membranes), bladder cancer, rheumatoid arthritis, Lyme disease and lipomas, Down's syndrome and asthma are but a few.

Author Bio:

Patricia Howitt

I have degrees in Arts (Languages and Philosophy) and Law. My first job was with the NZ Department of Customs. Thanks to help from the government's top legal advisors, I was able to fill the Office Solicitor's role while studying for my law degree - drafting law, preparing cases for hearing, and providing general legal advice. It was a huge learning curve, but it set me up early for a career in government.

Once qualified, I worked in the office of the Crown Prosecutor to widen my experience, and moved to the legal division of the Ministry of Transport, dealing with Maritime issues, Traffic and Transport Licensing. I also trained Senior Traffic Officers in prosecution techniques.

I was headhunted into the newly formed Accident Compensation Corporation, administering a "world first" system to replace accident litigation with statutory compensation for accidental injury. Medical issues dominated this arena, so we worked closely with the Corporation's medical advisors on the many medico-legal questions.

I became one of the Corporation's leading advocates on Appeal and was appointed as a Review Officer to hear and decide complaints about Corporation decisions. There was nothing informal about this process, or its outcome - Review Officers filed fully reasoned decisions that were subject to appeal to a High Court Judge if the claimant was not satisfied. When I left the Corporation I was Regional Solicitor for its central North Island region, responsible for all of its legal work and Review hearings.

For two years I taught part-time in the Waikato Polytechnic, lecturing in Business Law for the NZ Society of Accountants' Diploma in Business Studies. I sat for the Introductory Certificate in Business Computing, and applied it to secretarial and publishing work for our Hospital Trust and the Breed Club I belonged to. Soon the Internet beckoned. I came online in June 1996. The following year I started a small graphic design business in our nearest town. I was contracted to create all the website graphics for my ISP Voyager, owned by the Australian ISP OzEmail, and for some of its clients, but sadly Voyager was sold in 1998 and disbanded soon afterwards.

For family reasons, I brought my business home in 2002 and now concentrate solely on the Net. I freelance in graphics and web design and still find time to indulge my passions for art and writing.

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